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Tuesday, December 31, 2013

By Rob Sutter


What is it that can be said about the P1D1 gene as far as brain cancer, in general, is concerned? This particular gene entails the signaling of insulin and mitochondrial function within the brain alike, meaning that it is an integral aspect that not many people are familiar with. For the longest time, it seems like this gene has only been focused on when it came to conditions like obesity and diabetes. However, it seems like this type of cancer will be one to take into account as well.

When looking at the way that this gene has been linked to brain cancer, is it any wonder as to why this has been the case? I do not think that anyone can argue with such a point, especially when you consider just how many therapies have been implemented certain aspects linked to other conditions. However, the idea that they can play into this one is worth the attention of various organizations, Voices against Brain Cancer included. You may be curious, though, about the importance of the P1D1 gene when regarding this type of cancer.

There was a report posted on Business Wire and it spoke, in detail, about the level of messenger RNA that can be found in the gene referred to as P1D1. For those who do not know, this can play greatly in terms of two conditions in particular: medulloblastomas and gliomas. P1D1 is needed in order to inhibit the growth of cells in said conditions, which speaks volumes about their functionality. With a study set in place, what can be said about this gene in relation to cancer in general?

As it seems, higher levels of P1D1 mRNA have been directly correlated to increased survival rates in patient. The report spoke about this, saying that P1D1 - when in higher amounts - actually aided in the way of tumor cell death and brought down the amount of proliferation in regards to cells in question. It's apparent that several adults were tested in this experiment and, by and large, survival rates shot up. This goes to show that the presence of this gene is far more useful in the medical field than many would probably give it credit for.

It seems as though these therapies possess great potential, meaning that results are more than worth the attention they can bring. This is especially true when considering the detrimental nature that this condition has entailed. It goes without saying that many individuals have been impacted by it, so it also goes without saying that surgery on its own may not create the greatest long-term results. This may be case where focusing on the P1D1 gene is a strong idea.




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